

The 49ers ruled Christian Kirk out for Monday night against Washington at 1:08 p.m. Pacific, five days after opening his practice window off injured reserve, and elevated linebacker Jalen Graham and receiver Malik Turner from the practice squad in the same release. The club has 21 days from Oct. 15 to put Kirk on the 53, and the only game left inside that window after Monday is at Atlanta on Oct. 25; the bye follows. The inactive list posted at 3:44 p.m.: Kurtis Rourke, Enrique Cruz Jr., Deebo Samuel, Garret Wallow, Marques Sigle, Nick Bosa and Naquan Jones. Mike Evans, Gracen Halton, Mykel Williams, Siran Neal and Upton Stout, all questionable Saturday, are active, and Kyle Juszczyk returns. The receivers in uniform are Evans, Brandin Cooks, Jacob Cowing, Jordan Watkins and Turner. Graham, a 2023 seventh-round pick with 15 career games, covers for Garret Wallow and the suspended Dre Greenlaw. Washington activated three players from injured reserve and put two on it.

Kyle Shanahan ruled out Nick Bosa (knee, calf), Deebo Samuel (hamstring), Garret Wallow (hamstring) and Marques Sigle (ankle) for Monday night against Washington. Mike Evans, Christian Kirk, Gracen Halton, Mykel Williams, Upton Stout and Siran Neal are questionable. Kyle Juszczyk is expected to play, eight days after missing Seattle. Asked whether Kirk will be activated off injured reserve, Shanahan said \"Possibly\"; the 53 is full, so that takes a corresponding move.

Kyle Juszczyk was a full participant in Friday's practice, 12 days after a hyperextended knee and bone bruise, and John Lynch told KNBR there is a chance he plays Washington on Monday. Christian Kirk was limited; activating him would cost someone a spot on a full 53. Nick Bosa, now listed with knee and calf, did not practice, nor did Mike Evans, Gracen Halton or Romello Height. Lynch said trade calls have picked up and that George Kittle asked him about Khalil Mack. Kittle said he asks all the time.

The 49ers opened Christian Kirk's 21-day practice window on Thursday, 81 days after he strained a calf on the first day of training camp, and Kyle Shanahan said he was ready to go after a strong weekend. Mike Evans did not practice with ribs and Achilles soreness, which leaves the receiver room thinner than Monday's count. Shanahan called injured reserve for Deebo Samuel 'a possibility.' Nick Bosa, James Thompson Jr. and Gracen Halton sat out Thursday; Kyle Juszczyk was limited. The club promoted Ogbo Okoronkwo to the 53 into the spot Greenlaw's suspension opened and signed linebacker Eugene Asante to the practice squad. Washington is at Levi's Stadium on Monday night.

Kyle Shanahan said on a conference call Monday that Deebo Samuel's hamstring \"got him pretty good\" and he will miss some time, so the 49ers will most likely activate a practice-squad receiver for Washington next Monday night. The NFL suspended Dre Greenlaw one game without pay for head-butting Seattle's Ernest Jones IV; his appeal is heard Tuesday, and his 2025 appeal of a one-game suspension was denied. Garret Wallow strained a hamstring and is out at least a couple of weeks, which leaves four linebackers. Nick Bosa, Kyle Juszczyk and James Thompson Jr. have a chance for Week 6, and Nick Martin is getting close.

San Francisco (4-0) plays at Seattle (3-1) at 1:25 p.m. Pacific on FOX. The 49ers scored three field goals and no touchdowns in last season's two losses to the Seahawks, 13-3 in Week 18 and 41-6 in the divisional round. Brock Purdy has not been sacked this season. Nick Bosa, James Thompson Jr., Kyle Juszczyk and Marques Sigle are out; Upton Stout is questionable; Mykel Williams makes his season debut. Ten men to watch.

The 49ers activated Mykel Williams off the physically unable to perform list on Saturday and removed his questionable tag for Sunday at Seattle. Ogbo Okoronkwo, released Friday to open the roster spot, signed back to the practice squad and was elevated for the game along with tight end Jack Stoll. Matthew Judon was released from the practice squad to make room, per NBC Sports. Nick Bosa, James Thompson Jr., Kyle Juszczyk and Marques Sigle are out; Upton Stout is questionable.

The 49ers released defensive lineman Ogbo Okoronkwo on Friday, leaving 52 on the active roster, and Kyle Shanahan said Mykel Williams will be activated from the physically unable to perform list on Saturday. Nick Bosa, Kyle Juszczyk, Marques Sigle and James Thompson Jr. are out at Seattle. Upton Stout, who did not practice Friday, and Williams are questionable. Mike Evans practiced on a limited basis and has no game designation.

Upton Stout returned to practice Thursday in a blue no-contact jersey and was limited on the club's report; Kyle Shanahan said there is potential he plays Sunday. Mike Evans did not practice after being limited Wednesday. Shanahan said Mykel Williams should be good to go. John Lynch told KNBR that Kyle Juszczyk's injury looked like a torn ACL and is a bone bruise. The 49ers reached an injury settlement with Dante Pettis.

Mykel Williams, back from a torn ACL, was limited Wednesday and told reporters he is ready to play. The 49ers opened his practice window Sept. 30 and must activate him by Oct. 21; the 53 is full, so activating him takes a move. Nick Bosa, James Thompson Jr., Kyle Juszczyk, Marques Sigle and Upton Stout did not practice. Xavier Smith joined the practice squad and Dante Pettis went on practice squad injured reserve.

Kyle Shanahan said Monday that Kyle Juszczyk has a hyperextended knee and a bone bruise and will miss a few weeks, that Marques Sigle has a high ankle sprain, and that Upton Stout is day to day with a sprained AC joint. Brayden Willis, Luke Farrell and George Kittle share the fullback's work. Nick Bosa and James Thompson Jr. are probably out again at Seattle; Mykel Williams could be activated.

San Francisco is 4-0 after a 24-14 win over Denver. It was 3-3 at halftime and the 49ers had punted four times, been stopped on fourth down and had a field goal blocked before Siran Neal forced and recovered a fumble on a punt return at the Denver 28. Touchdowns followed on three straight possessions, the last a 56-yard George Kittle catch and run with 2:15 left. Purdy was 19 of 30 for 218 yards and two touchdowns and was not sacked for the fourth straight game. Mike Evans played 39 of 66 snaps with a rib injury and led the team with 76 receiving yards. Kyle Juszczyk (knee), Upton Stout (shoulder) and Marques Sigle (ankle) were hurt, and none has a diagnosis.

Eddy Piñeiro has not kicked in a practice since the Melbourne game week ended, and Matt Maiocco reported Saturday that he will kick against Miami anyway. San Francisco auditioned Younghoe Koo and Greg Joseph and kept neither, so it carries one kicker into the home opener, counted across all four of the club's roster lists at 2:57pm. Ogbo Okoronkwo was promoted to the active roster and De'Zhaun Stribling went on injured reserve three days after ankle surgery. The league fined Kyle Juszczyk $20,033 and Jake Tonges $9,266 for plays in Melbourne.

De'Zhaun Stribling, the wide receiver San Francisco took with the 33rd pick in April, was hurt in his first professional game and the 49ers have published nothing about him since. The official participation report has him at 21 offensive snaps of 65, which is 32 percent. Counted against the 26 plays from scrimmage San Francisco ran before the snap he was injured on, it is 21 of 26, or 81 percent. The count reconciles to 65 at the end of the game once the second-quarter roughing-the-passer penalty is included, which is the check on it. He was not targeted on any of the 21. Six 49ers receivers took an offensive snap in Melbourne: Mike Evans 49, Demarcus Robinson 41, Deebo Samuel 27, Stribling 21, Jacob Cowing 5 and KhaDarel Hodge 1. Tight end Luke Farrell played 46, more than every receiver but Evans, and fullback Kyle Juszczyk played 33, more than Samuel. Four of the five other receivers who played are 30 or older. Kyle Shanahan said after the game that the Achilles was checked and intact and that the club was not sure of the magnitude of the ankle injury; further testing waited on the flight home, which David Bonilla of 49ers Webzone clocked at 13 hours 46 minutes, landing at SFO at 3:06 p.m. Friday. San Francisco's next game is Miami at Levi's Stadium on Sunday, September 20, at 1:25 p.m. Pacific, and the 49ers traded down twice in April, first with Miami, to reach the pick they spent on Stribling. No take filed.

San Francisco's Week 1 injury report, read live at 49ers.com and again at therams.com on Thursday morning Pacific, carries eleven San Francisco names and two designations. Alfred Collins, listed at defensive line with a knee, is Out; the club's own item says he tore a patellar tendon and will miss the 2026 season. James Thompson Jr., hamstring, is Questionable after going from did not participate to limited. The other nine, including Nick Bosa, Kyle Juszczyk, Dre Greenlaw and George Kittle, carry no game designation, and Upton Stout is the only full participant on the page. Kittle is limited on every practice day the report carries a value for, with no designation, on an Achilles tendon he tore on January 11. The grid's Monday column is empty on all eighteen rows across both clubs, while the club's own news item describes three Melbourne practices. The Rams' half has filled since Wednesday: Aaron Donald is Out, listed not injury related and resting, and the other six Los Angeles names carry the dash the legend defines as not listed. Kyle Shanahan on Bosa and Kittle: 'We've got to be smart with that.' Kickoff is 5:35 p.m. Pacific at the Melbourne Cricket Ground. One take filed.

San Francisco opens the 2026 season against Los Angeles at the Melbourne Cricket Ground on Thursday at 5:35 p.m. Pacific, 10:35 a.m. Friday in Melbourne, on Netflix, with radio on KSFO 810 AM and KSAN 107.7 FM. The club's roster page, counted in a browser on Thursday morning, carries 53 active players and exactly nine rookies. Seven of those nine are listed second at a position on the club's own website depth chart, stamped September 8 and labelled unofficial; the other two are listed third. None is listed first. The club's final injury report, published at 12:23 a.m. Pacific Thursday, issued two game designations: DL Alfred Collins out with a knee, which Kyle Shanahan said is a torn patellar tendon that ends his season, and rookie DL James Thompson Jr. questionable with a hamstring. Nick Bosa, knee, and George Kittle, achilles, were limited at all three Melbourne practices and carry no designation. Shanahan on the two of them: 'We've got to be smart with that. They both look great but we've definitely got to be smart with that.' Bosa said he is '100 percent ready to go for the first game.' Luke Gifford, Renardo Green, Dre Greenlaw, Gracen Halton and Romello Height all progressed to full participation at the last practice. Kyle Juszczyk stayed limited with a finger. Los Angeles ruled out Aaron Donald, filed under rest. Inactives land 90 minutes before kickoff. Ten players to watch, and the club's own chart still lists two men who cannot play.

San Francisco practised for the last time in training camp on Tuesday morning and Kyle Shanahan said afterwards that the left guard competition is close to being decided between Connor Colby and Carver Willis, with Robert Jones removed from it by a calf injury Shanahan put at around the Australia trip. Matt Maiocco had Willis taking the first-team snaps. Dominick Puni practised and then reported residual symptoms and is most likely back in the concussion protocol. Shanahan named Christian Kirk and Vederian Lowe as possible candidates to start the season on injured reserve, hedging both. Mike Evans, Jacob Cowing, Upton Stout, Romello Height, Kyle Juszczyk, Kirk, Kurtis Rourke and Nick Bosa did not practise across two published absence lists that do not match. Height's injury is an ankle and Juszczyk's finger is fractured. The 49ers play at Las Vegas on Thursday at 5:00 p.m. PDT and the roster is due at 53 at 3:00 p.m. PT on Sunday.